putative novel insertion sequence elements in prokaryotic genomes

mutationdetection

digIS: in direction of detecting distant and putative novel insertion sequence components in prokaryotic genomes

Background: The insertion sequence components (IS components) symbolize the smallest and probably the most plentiful cell components in prokaryotic genomes. It has been proven that they play a big position in genome group and evolution. To higher perceive their perform within the host genome, it’s fascinating to have an efficient detection and annotation instrument.

This want turns into much more essential when contemplating rapid-growing genomic and metagenomic information. The present instruments for IS components detection and annotation are normally based mostly on evaluating sequence similarity with a database of recognized IS households. Thus, they’ve restricted skill to find distant and putative novel IS components.

Outcomes: On this paper, we current digIS, a software program instrument based mostly on profile hidden Markov fashions assembled from catalytic domains of transposases. It exhibits an excellent efficiency in detecting recognized IS components when examined on datasets with manually curated annotation. The principle contribution of digIS is in its skill to detect distant and putative novel IS components whereas sustaining a average degree of false positives. On this class it outperforms present instruments, particularly when examined on massive datasets of archaeal and bacterial genomes.

Conclusion: We offer digIS, a software program instrument utilizing a novel method based mostly on manually curated profile hidden Markov fashions, which is ready to detect distant and putative novel IS components. Though digIS can discover recognized IS components as effectively, we anticipate it for use primarily by scientists taken with discovering novel IS components.

The Worth of NOTCH2NLC Gene Detection and Pores and skin Biopsy within the Prognosis of Neuronal Intranuclear Inclusion Illness

The scientific manifestations of neuronal intranuclear inclusion illness (NIID) are heterogeneous, and the premortem prognosis is especially based mostly on pores and skin biopsy findings. Irregular GGC repeat expansions in NOTCH2NLC was not too long ago recognized in familial and sporadic NIID. The comparability of diagnostic worth between irregular GGC repeat expansions of NOTCH2NLC and pores and skin biopsy has not been performed but.

On this examine, pores and skin biopsy was carried out in 10 suspected grownup NIID sufferers with scientific and imaging manifestations, and GGC repeat measurement in NOTCH2NLC was additionally screened by repeat primed-PCR and GC-rich PCR. We discovered that 5 instances had ubiquitin-immunolabelling intranuclear inclusion our bodies by pores and skin biopsy, and all of them have been recognized with irregular GGC repeat expansions in NOTCH2NLC, amongst whom 4 sufferers confirmed typical linear hyperintensity at corticomedullary junction on DWI.

Five (5/10) NIID sufferers have been recognized by mixture of NOTCH2NLC gene detection, pores and skin biopsy or mixture of NOTCH2NLC, and typical MRI findings. The diagnostic efficiency of NOTCH2NLC gene detection was extremely in keeping with that of pores and skin biopsy (Kappa = 1). The unexplained headache was firstly reported as a brand new early phenotype of NIID. These findings point out that NOTCH2NLC gene detection is required to be a complement within the diagnose circulation of NIID and likewise could also be used instead technique to pores and skin biopsy particularly in Asian inhabitants.

 

mutationdetection
mutationdetection

EpCAM Antigen

E64B00107 0.1mg
EUR 343

Human epithelial specific antigen,ESA ELISA Kit

CN-04610H1 96T
EUR 442

Human epithelial specific antigen,ESA ELISA Kit

CN-04610H2 48T
EUR 293

Human epithelial specific antigen(ESA)ELISA Kit

GA-E1696HM-48T 48T
EUR 289

Human epithelial specific antigen(ESA)ELISA Kit

GA-E1696HM-96T 96T
EUR 466

Human epithelial specific antigen,ESA ELISA Kit

201-12-1680 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Anti-Ep-CAM/Epithelial Specific Antigen antibody

STJ16100363 1 mL
EUR 868

Human epithelial specific antigen(ESA)ELISA Kit

QY-E01682 96T
EUR 361

Recombinant Epithelial Cell Adhesion Molecule (EPCAM)

4-RPB283Ga01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Chicken Epithelial Cell Adhesion Molecule expressed in: E.coli

Recombinant Epithelial Cell Adhesion Molecule (EPCAM)

4-RPB283Hu01
  • EUR 440.48
  • EUR 221.00
  • EUR 1376.80
  • EUR 525.60
  • EUR 951.20
  • EUR 358.00
  • EUR 3292.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Epithelial Cell Adhesion Molecule expressed in: E.coli

Recombinant Epithelial Cell Adhesion Molecule (EPCAM)

4-RPB283Po01
  • EUR 548.00
  • EUR 250.00
  • EUR 1780.00
  • EUR 660.00
  • EUR 1220.00
  • EUR 430.00
  • EUR 4300.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pig Epithelial Cell Adhesion Molecule expressed in: E.coli

Human Epithelial cell adhesion molecule (EPCAM)

1-CSB-EP007717HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Epithelial cell adhesion molecule(EPCAM),partial expressed in E.coli

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx129957
  • EUR 467.00
  • EUR 133.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx125330
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx112318
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

20-abx123431
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx104775
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

abx037446-100ug 100 ug
EUR 391

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

abx037447-100ug 100 ug
EUR 391

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx011925-100ul 100 ul
EUR 411

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

abx030033-400ul 400 ul
EUR 523

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

abx030033-80l 80 µl
EUR 286

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx430513-200ul 200 ul
EUR 384

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx172278
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx270202
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx224065-100ug 100 ug
EUR 411

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx338680
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx159488-100ul 100 ul
EUR 467

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx242428
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx242433
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx214622
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx232799-100ug 100 ug
EUR 509

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx176308
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx331190-100ul 100 ul
EUR 425

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx327226
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx324346
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC942041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF594 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC942041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF594 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCA2041-250 250uL
EUR 394
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), APC conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC812041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC812041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCAP2041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCAP2041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC472041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF647 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC472041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF647 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC432041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF543 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC432041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF543 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC882041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF488A conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC882041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF488A conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCH2041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCH2041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCP2041-250 250uL
EUR 394
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), PerCP conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC042041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405S conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC042041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405S conjugate, Concentration: 0.1mg/mL

Chicken Epithelial Cell Adhesion Molecule (EPCAM) Protein

20-abx168032
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (FITC)

20-abx270500
  • EUR 523.00
  • EUR 606.00
  • EUR 300.00
  • EUR 940.00
  • EUR 384.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (APC)

20-abx270732
  • EUR 704.00
  • EUR 829.00
  • EUR 370.00
  • EUR 1330.00
  • EUR 495.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (PE)

20-abx270964
  • EUR 606.00
  • EUR 718.00
  • EUR 328.00
  • EUR 1135.00
  • EUR 439.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Pig Epithelial Cell Adhesion Molecule (EPCAM) Protein

20-abx167541
  • EUR 759.00
  • EUR 300.00
  • EUR 2388.00
  • EUR 913.00
  • EUR 537.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (FITC)

abx140496-100tests 100 tests
EUR 425

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (PE)

abx140492-100tests 100 tests
EUR 481

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCR2041-250 250uL
EUR 394
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), RPE conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNUB2041-100 100uL
EUR 264
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Concentration: 0.2mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNUB2041-50 50uL
EUR 405
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), 1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNUB2041-500 500uL
EUR 513
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Concentration: 0.2mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC612041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF660R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC612041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF660R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC682041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF568 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC682041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF568 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC702041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF770 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC702041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF770 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC052041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405M conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC052041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405M conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC552041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF555 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC552041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF555 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC402041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF640R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC402041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF640R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC802041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC802041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCB2041-100 100uL
EUR 233
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Biotin conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCB2041-500 500uL
EUR 545
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Biotin conjugate, Concentration: 0.1mg/mL

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (HRP)

20-abx335604
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (FITC)

20-abx335605
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (Biotin)

20-abx335606
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Epithelial Cell Adhesion Molecule (EPCAM) Protein

20-abx652155
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Chicken Epithelial cell adhesion molecule, EPCAM ELISA KIT

ELI-04242c 96 Tests
EUR 928

Human Epithelial cell adhesion molecule, EPCAM ELISA KIT

ELI-04243h 96 Tests
EUR 824

Bovine Epithelial cell adhesion molecule, EPCAM ELISA KIT

ELI-04246b 96 Tests
EUR 928

Mouse Epithelial cell adhesion molecule, Epcam ELISA KIT

ELI-04247m 96 Tests
EUR 865

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

SEB283Hu-10x96wellstestplate 10x96-wells test plate
EUR 4502.43
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

SEB283Hu-1x48wellstestplate 1x48-wells test plate
EUR 458.44
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

SEB283Hu-1x96wellstestplate 1x96-wells test plate
EUR 612.05
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

SEB283Hu-5x96wellstestplate 5x96-wells test plate
EUR 2454.23
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

4-SEB283Hu
  • EUR 4553.00
  • EUR 2405.00
  • EUR 613.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Chicken)

4-PAB283Ga01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Epithelial Cell Adhesion Molecule (EPCAM)

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Pig)

4-PAB283Po01
  • EUR 267.00
  • EUR 2826.00
  • EUR 697.00
  • EUR 338.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Epithelial Cell Adhesion Molecule (EPCAM)

Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody (Human)

4-MAB283Hu21
  • EUR 247.00
  • EUR 2516.00
  • EUR 626.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Epithelial Cell Adhesion Molecule (EPCAM)

Human Epithelial cell adhesion molecule(EPCAM) ELISA kit

CSB-EL007717HU-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Epithelial cell adhesion molecule (EPCAM) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Epithelial cell adhesion molecule(EPCAM) ELISA kit

1-CSB-EL007717HU
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Epithelial cell adhesion molecule(EPCAM) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Cow Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx516210-96tests 96 tests
EUR 911

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx516212-96tests 96 tests
EUR 668

Mouse Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx516213-96tests 96 tests
EUR 707

Rat Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx516215-96tests 96 tests
EUR 668

Human Epithelial Cell Adhesion Molecule, EPCAM ELISA Kit

DEIA244 5 plates
EUR 1344
Description: The human EPCAM ELISA kit is for the quantitative determination of human EPCAM.

Human EPCAM/ Epithelial cell adhesion molecule ELISA Kit

E0800Hu 1 Kit
EUR 571

Human Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit

20-abx492586
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx254058-96tests 96 tests
EUR 707

Pig Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx361484-96tests 96 tests
EUR 825

Rabbit Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx363660-96tests 96 tests
EUR 825

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx350740-96tests 96 tests
EUR 668

Monkey Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx359768-96tests 96 tests
EUR 825

Chicken Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx356953-96tests 96 tests
EUR 825

Human Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit

abx196638-96tests 96 tests
EUR 825

Mouse Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit

abx196938-96tests 96 tests
EUR 825

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

20-abx151423
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

EPCAM Epithelial Cell Adhesion Molecule Human Recombinant Protein

PROTP16422 Regular: 20ug
EUR 317
Description: EPCAM Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 267 amino acids (24-265 a.a.) and having a molecular mass of 30.1kDa.;EPCAM is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Mouse EPCAM(Epithelial Cell Adhesion Molecule) ELISA Kit

EM1005 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.047 ng/ml

Prostate Specific Antigen Std Grade Antigen

VAng-Cr3891-1mg 1 mg
EUR 504
Description: Prostate Specific Antigen Std Grade Antigen, Host/Source: Human Seminal Fluid. The purity is detected by salt precipitation.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Chicken), APC

4-PAB283Ga01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with APC.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Chicken), Biotinylated

4-PAB283Ga01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with Biotin.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Chicken), Cy3

4-PAB283Ga01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with Cy3.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Chicken), FITC

4-PAB283Ga01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with FITC.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Chicken), HRP

4-PAB283Ga01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with HRP.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Chicken), PE

4-PAB283Ga01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with PE.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Pig), APC

4-PAB283Po01-APC
  • EUR 376.00
  • EUR 3707.00
  • EUR 1020.00
  • EUR 483.00
  • EUR 232.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with APC.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Pig), Biotinylated

4-PAB283Po01-Biotin
  • EUR 334.00
  • EUR 2776.00
  • EUR 806.00
  • EUR 412.00
  • EUR 228.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with Biotin.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Pig), Cy3

4-PAB283Po01-Cy3
  • EUR 459.00
  • EUR 4901.00
  • EUR 1319.00
  • EUR 602.00
  • EUR 267.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with Cy3.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Pig), FITC

4-PAB283Po01-FITC
  • EUR 320.00
  • EUR 2985.00
  • EUR 836.00
  • EUR 406.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with FITC.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Pig), HRP

4-PAB283Po01-HRP
  • EUR 342.00
  • EUR 3229.00
  • EUR 901.00
  • EUR 435.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with HRP.

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Pig), PE

4-PAB283Po01-PE
  • EUR 320.00
  • EUR 2985.00
  • EUR 836.00
  • EUR 406.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with PE.

Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody (Human), APC

4-MAB283Hu21-APC
  • EUR 346.00
  • EUR 3284.00
  • EUR 914.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with APC.

Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody (Human), Biotinylated

4-MAB283Hu21-Biotin
  • EUR 312.00
  • EUR 2466.00
  • EUR 729.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with Biotin.

Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody (Human), Cy3

4-MAB283Hu21-Cy3
  • EUR 420.00
  • EUR 4337.00
  • EUR 1178.00
  • EUR 546.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with Cy3.

Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody (Human), FITC

4-MAB283Hu21-FITC
  • EUR 297.00
  • EUR 2647.00
  • EUR 751.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with FITC.

Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody (Human), HRP

4-MAB283Hu21-HRP
  • EUR 316.00
  • EUR 2862.00
  • EUR 809.00
  • EUR 398.00
  • EUR 207.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with HRP.

Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody (Human), PE

4-MAB283Hu21-PE
  • EUR 297.00
  • EUR 2647.00
  • EUR 751.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Epithelial Cell Adhesion Molecule (EPCAM). This antibody is labeled with PE.

ELISA kit for Human EPCAM (Epithelial Cell Adhesion Molecule)

ELK1968 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Epithelial Cell Adhesion Molecule from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

CLIA kit for Mouse EPCAM (Epithelial Cell Adhesion Molecule)

E-CL-M0286 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Mouse EPCAM (Epithelial Cell Adhesion Molecule) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Mouse EPCAM (Epithelial Cell Adhesion Molecule)

E-EL-M0470 1 plate of 96 wells
EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Mouse EPCAM (Epithelial Cell Adhesion Molecule) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human Epithelial cell adhesion molecule (EPCAM)

KTE62402-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Human Epithelial cell adhesion molecule (EPCAM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Epithelial cell adhesion molecule (EPCAM)

KTE62402-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Epithelial cell adhesion molecule (EPCAM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Epithelial cell adhesion molecule (EPCAM)

KTE62402-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Human Epithelial cell adhesion molecule (EPCAM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

anti-Prostate Specific Antigen

YF-PA10281 50 ug
EUR 363
Description: Mouse polyclonal to Prostate Specific Antigen

anti-Prostate Specific Antigen

YF-PA10282 100 ug
EUR 403
Description: Rabbit polyclonal to Prostate Specific Antigen

Epithelium Specific Antigen antibody

10R-E126A 50 ug
EUR 418
Description: Mouse monoclonal Epithelium Specific Antigen antibody

Prostate-specific Antigen Antibody

20-abx013184
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Prostate-specific antigen Antibody

abx020585-1mg 1 mg
EUR 481

Prostate-specific antigen Antibody

abx020586-1mg 1 mg
EUR 704

Prostate-specific antigen Antibody

abx020587-1mg 1 mg
EUR 801

Prostate-specific antigen Antibody

abx020588-1mg 1 mg
EUR 801

Prostate-specific antigen Antibody

abx020591-1mg 1 mg
EUR 551

Prostate-specific antigen Antibody

abx020592-1mg 1 mg
EUR 551

Prostate-specific antigen Antibody

abx020593-1mg 1 mg
EUR 551

Prostate-specific antigen Antibody

abx020594-1mg 1 mg
EUR 551

Prostate-specific antigen Antibody

abx020595-1mg 1 mg
EUR 551

Prostate-specific antigen Antibody

abx020596-1mg 1 mg
EUR 662

Prostate-specific antigen Antibody

abx020597-1mg 1 mg
EUR 509

Prostate-specific antigen Antibody

abx020598-1mg 1 mg
EUR 509

Prostate-specific antigen Antibody

abx020599-1mg 1 mg
EUR 509

Prostate-specific antigen Antibody

abx020600-1mg 1 mg
EUR 509

Gene Expression Modifications in a Mannequin Neuron Cell Line Uncovered to Autoantibodies from Sufferers with Traumatic Mind Damage and/or Sort 2 Diabetes

Traumatic mind damage and grownup sort 2 diabetes mellitus are every related to the late prevalence of accelerated cognitive decline and Parkinson’s illness via unknown mechanisms. Beforehand, we reported elevated circulating agonist autoantibodies concentrating on the 5-hydroxytryptamine 2A receptor in plasma from subsets of Parkinson’s illness, dementia, and diabetic sufferers struggling with microvascular problems.

Right here, we use a mannequin neuron, mouse neuroblastoma (N2A) cell line, to check messenger RNA expression adjustments following transient publicity to traumatic mind damage and/or sort 2 diabetes mellitus plasma harboring agonist 5-hydroxytryptamine 2A receptor autoantibodies.

We now report involvement of the mitochondrial dysfunction pathway and Parkinson’s illness pathways in autoantibody-induced gene expression adjustments occurring in neuroblastoma cells. Useful gene classes upregulated considerably included cell dying, cytoskeleton-microtubule perform, actin polymerization or depolymerization, regulation of cell oxidative stress, mitochondrial perform, immune perform, protein metabolism, and vesicle perform.

Gene classes considerably downregulated included microtubule perform, cell adhesion, neurotransmitter launch, dopamine metabolism synaptic plasticity, upkeep of neuronal differentiation, mitochondrial perform, and cell signaling.

Taken collectively, these outcomes recommend that agonist 5-hydroxytryptamine receptor autoantibodies (which enhance in Parkinson’s illness and different types of neurodegeneration) mediate a coordinating program of gene expression adjustments in a mannequin neuron which predispose to neuro-apoptosis and are linked to human neurodegenerative ailments pathways.

Novel Alzheimer’s illness danger variants recognized based mostly on whole-genome sequencing of APOE ε4 carriers

Alzheimer’s illness (AD) is a progressive neurodegenerative illness related to a fancy genetic etiology. Moreover the apolipoprotein E ε4 (APOE ε4) allele, a couple of dozen different genetic loci related to AD have been recognized via genome-wide affiliation research (GWAS) performed primarily in people of European ancestry.

 

Lately, a number of GWAS carried out in different ethnic teams have proven the significance of replicating research that establish beforehand established danger loci and looking for novel danger loci. APOE-stratified GWAS have yielded novel AD danger loci that may be masked by, or be depending on, APOE alleles.

 

We carried out whole-genome sequencing (WGS) on DNA from blood samples of 331 AD sufferers and 169 aged controls of Korean ethnicity who have been APOE ε4 carriers. Based mostly on WGS information, we designed a custom-made AD chip (cAD chip) for additional evaluation on an impartial set of 543 AD sufferers and 894 aged controls of the identical ethnicity, no matter their APOE ε4 allele standing.

Mixed evaluation of WGS and cAD chip information revealed that SNPs rs1890078 (P = 6.64E-07) and rs12594991 (P = 2.03E-07) in SORCS1 and CHD2 genes, respectively, are novel genetic variants amongst APOE ε4 carriers within the Korean inhabitants.

As well as, 9 doable novel variants that have been uncommon in people of European ancestry however frequent in East Asia have been recognized. This examine demonstrates that APOE-stratified evaluation is vital for understanding the genetic background of AD in numerous populations.

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