putative novel insertion sequence elements in prokaryotic genomes

mutationdetection

digIS: in direction of detecting distant and putative novel insertion sequence components in prokaryotic genomes

Background: The insertion sequence components (IS components) symbolize the smallest and probably the most plentiful cell components in prokaryotic genomes. It has been proven that they play a big position in genome group and evolution. To higher perceive their perform within the host genome, it’s fascinating to have an efficient detection and annotation instrument.

This want turns into much more essential when contemplating rapid-growing genomic and metagenomic information. The present instruments for IS components detection and annotation are normally based mostly on evaluating sequence similarity with a database of recognized IS households. Thus, they’ve restricted skill to find distant and putative novel IS components.

Outcomes: On this paper, we current digIS, a software program instrument based mostly on profile hidden Markov fashions assembled from catalytic domains of transposases. It exhibits an excellent efficiency in detecting recognized IS components when examined on datasets with manually curated annotation. The principle contribution of digIS is in its skill to detect distant and putative novel IS components whereas sustaining a average degree of false positives. On this class it outperforms present instruments, particularly when examined on massive datasets of archaeal and bacterial genomes.

Conclusion: We offer digIS, a software program instrument utilizing a novel method based mostly on manually curated profile hidden Markov fashions, which is ready to detect distant and putative novel IS components. Though digIS can discover recognized IS components as effectively, we anticipate it for use primarily by scientists taken with discovering novel IS components.

The Worth of NOTCH2NLC Gene Detection and Pores and skin Biopsy within the Prognosis of Neuronal Intranuclear Inclusion Illness

The scientific manifestations of neuronal intranuclear inclusion illness (NIID) are heterogeneous, and the premortem prognosis is especially based mostly on pores and skin biopsy findings. Irregular GGC repeat expansions in NOTCH2NLC was not too long ago recognized in familial and sporadic NIID. The comparability of diagnostic worth between irregular GGC repeat expansions of NOTCH2NLC and pores and skin biopsy has not been performed but.

On this examine, pores and skin biopsy was carried out in 10 suspected grownup NIID sufferers with scientific and imaging manifestations, and GGC repeat measurement in NOTCH2NLC was additionally screened by repeat primed-PCR and GC-rich PCR. We discovered that 5 instances had ubiquitin-immunolabelling intranuclear inclusion our bodies by pores and skin biopsy, and all of them have been recognized with irregular GGC repeat expansions in NOTCH2NLC, amongst whom 4 sufferers confirmed typical linear hyperintensity at corticomedullary junction on DWI.

Five (5/10) NIID sufferers have been recognized by mixture of NOTCH2NLC gene detection, pores and skin biopsy or mixture of NOTCH2NLC, and typical MRI findings. The diagnostic efficiency of NOTCH2NLC gene detection was extremely in keeping with that of pores and skin biopsy (Kappa = 1). The unexplained headache was firstly reported as a brand new early phenotype of NIID. These findings point out that NOTCH2NLC gene detection is required to be a complement within the diagnose circulation of NIID and likewise could also be used instead technique to pores and skin biopsy particularly in Asian inhabitants.

 

mutationdetection
mutationdetection

EpCAM Antigen

E64B00107 0.1mg
EUR 411.6

Human epithelial specific antigen,ESA ELISA Kit

CN-04610H1 96T
EUR 530.4

Human epithelial specific antigen,ESA ELISA Kit

CN-04610H2 48T
EUR 351.6

Human epithelial specific antigen,ESA ELISA Kit

201-12-1680 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human epithelial specific antigen(ESA)ELISA Kit

GA-E1696HM-48T 48T
EUR 346.8

Human epithelial specific antigen(ESA)ELISA Kit

GA-E1696HM-96T 96T
EUR 559.2

Human epithelial specific antigen(ESA)ELISA Kit

QY-E01682 96T
EUR 433.2

Anti-Ep-CAM/Epithelial Specific Antigen antibody

STJ16100363 1 mL
EUR 1041.6

Human epithelial specific antigen,ESA ELISA Kit

YLA2715HU-48T 48T
EUR 435

Human epithelial specific antigen,ESA ELISA Kit

YLA2715HU-96T 96T
EUR 562.5

Human Epithelial cell adhesion molecule (EPCAM)

1-CSB-EP007717HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Epithelial cell adhesion molecule(EPCAM),partial expressed in E.coli

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx104775
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx159488-100ul 100 ul
EUR 560.4

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx172278
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

20-abx123431
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx125330
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx129957
  • EUR 560.40
  • EUR 159.60
  • EUR 1612.80
  • EUR 760.80
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx112318
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx011925-100ul 100 ul
EUR 493.2

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

abx030033-400ul 400 ul
EUR 627.6

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

abx030033-80l 80 µl
EUR 343.2

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

abx037446-100ug 100 ug
EUR 469.2

Epithelial Cell Adhesion Molecule (EpCAM) Antibody

abx037447-100ug 100 ug
EUR 469.2

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx232799-100ug 100 ug
EUR 610.8

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx338680
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx331190-100ul 100 ul
EUR 510

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx270202
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx430513-200ul 200 ul
EUR 460.8

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx324346
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx327226
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx242428
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx242433
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx176308
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

20-abx214622
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Epithelial Cell Adhesion Molecule (EPCAM) Antibody

abx224065-100ug 100 ug
EUR 493.2

Recombinant Epithelial Cell Adhesion Molecule (EPCAM)

4-RPB283Ga01
  • EUR 636.10
  • EUR 294.00
  • EUR 2055.36
  • EUR 765.12
  • EUR 1410.24
  • EUR 501.60
  • EUR 4958.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Chicken Epithelial Cell Adhesion Molecule expressed in: E.coli

Recombinant Epithelial Cell Adhesion Molecule (EPCAM)

4-RPB283Hu01
  • EUR 528.58
  • EUR 265.20
  • EUR 1652.16
  • EUR 630.72
  • EUR 1141.44
  • EUR 429.60
  • EUR 3950.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Epithelial Cell Adhesion Molecule expressed in: E.coli

Recombinant Epithelial Cell Adhesion Molecule (EPCAM)

4-RPB283Po01
  • EUR 657.60
  • EUR 300.00
  • EUR 2136.00
  • EUR 792.00
  • EUR 1464.00
  • EUR 516.00
  • EUR 5160.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pig Epithelial Cell Adhesion Molecule expressed in: E.coli

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC942041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF594 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC942041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF594 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCA2041-250 250uL
EUR 472.8
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), APC conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC552041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF555 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC552041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF555 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC612041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF660R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC612041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF660R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCP2041-250 250uL
EUR 472.8
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), PerCP conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCR2041-250 250uL
EUR 472.8
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), RPE conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC402041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF640R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC402041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF640R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC432041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF543 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC432041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF543 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC052041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405M conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC052041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405M conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC812041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC812041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680R conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC802041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC802041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCH2041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCH2041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC042041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405S conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC042041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405S conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC682041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF568 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC682041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF568 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC702041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF770 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC702041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF770 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCAP2041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCAP2041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC882041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF488A conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC882041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF488A conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCB2041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Biotin conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNCB2041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Biotin conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC472041-100 100uL
EUR 279.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF647 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNC472041-500 500uL
EUR 654
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF647 conjugate, Concentration: 0.1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNUB2041-100 100uL
EUR 316.8
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Concentration: 0.2mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNUB2041-50 50uL
EUR 486
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), 1mg/mL

EpCAM / CD326 (Epithelial Marker) (EGP40/2041R) Antibody

BNUB2041-500 500uL
EUR 615.6
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Concentration: 0.2mg/mL

Chicken Epithelial Cell Adhesion Molecule (EPCAM) Protein

20-abx168032
  • EUR 878.40
  • EUR 343.20
  • EUR 2766.00
  • EUR 1062.00
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Pig Epithelial Cell Adhesion Molecule (EPCAM) Protein

20-abx167541
  • EUR 910.80
  • EUR 360.00
  • EUR 2865.60
  • EUR 1095.60
  • EUR 644.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (PE)

abx140492-100tests 100 tests
EUR 577.2

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (FITC)

abx140496-100tests 100 tests
EUR 510

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (HRP)

20-abx335604
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (FITC)

20-abx335605
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (Biotin)

20-abx335606
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Epithelial Cell Adhesion Molecule (EPCAM) Protein

20-abx652155
  • EUR 744.00
  • EUR 326.40
  • EUR 2230.80
  • EUR 878.40
  • EUR 543.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (FITC)

20-abx270500
  • EUR 627.60
  • EUR 727.20
  • EUR 360.00
  • EUR 1128.00
  • EUR 460.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (APC)

20-abx270732
  • EUR 844.80
  • EUR 994.80
  • EUR 444.00
  • EUR 1596.00
  • EUR 594.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Epithelial Cell Adhesion Molecule (EPCAM) Antibody (PE)

20-abx270964
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Human Epithelial cell adhesion molecule(EPCAM) ELISA kit

CSB-EL007717HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Epithelial cell adhesion molecule (EPCAM) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Epithelial cell adhesion molecule(EPCAM) ELISA kit

1-CSB-EL007717HU
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Epithelial cell adhesion molecule(EPCAM) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Epithelial Cell Adhesion Molecule, EPCAM ELISA Kit

DEIA244 5 plates
EUR 1612.8
Description: The human EPCAM ELISA kit is for the quantitative determination of human EPCAM.

Human EPCAM/ Epithelial cell adhesion molecule ELISA Kit

E0800Hu 1 Kit
EUR 685.2

Mouse EPCAM(Epithelial Cell Adhesion Molecule) ELISA Kit

EM1005 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.047 ng/ml

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

20-abx151423
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit

abx196638-96tests 96 tests
EUR 990

Mouse Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit

abx196938-96tests 96 tests
EUR 990

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx350740-96tests 96 tests
EUR 801.6

Rabbit Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx363660-96tests 96 tests
EUR 990

Chicken Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx356953-96tests 96 tests
EUR 990

Monkey Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx359768-96tests 96 tests
EUR 990

Pig Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx361484-96tests 96 tests
EUR 990

Cow Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx516210-96tests 96 tests
EUR 1093.2

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx516212-96tests 96 tests
EUR 801.6

Mouse Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx516213-96tests 96 tests
EUR 848.4

Rat Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx516215-96tests 96 tests
EUR 801.6

Human Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit

20-abx492586
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

abx254058-96tests 96 tests
EUR 848.4

Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody (Human)

4-MAB283Hu21
  • EUR 296.40
  • EUR 3019.20
  • EUR 751.20
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Epithelial Cell Adhesion Molecule (EPCAM)

Chicken Epithelial cell adhesion molecule, EPCAM ELISA KIT

ELI-04242c 96 Tests
EUR 1113.6

Human Epithelial cell adhesion molecule, EPCAM ELISA KIT

ELI-04243h 96 Tests
EUR 988.8

Bovine Epithelial cell adhesion molecule, EPCAM ELISA KIT

ELI-04246b 96 Tests
EUR 1113.6

Mouse Epithelial cell adhesion molecule, Epcam ELISA KIT

ELI-04247m 96 Tests
EUR 1038

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Chicken)

4-PAB283Ga01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Epithelial Cell Adhesion Molecule (EPCAM)

Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody (Pig)

4-PAB283Po01
  • EUR 320.40
  • EUR 3391.20
  • EUR 836.40
  • EUR 405.60
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Epithelial Cell Adhesion Molecule (EPCAM)

EPCAM Epithelial Cell Adhesion Molecule Human Recombinant Protein

PROTP16422 Regular: 20ug
EUR 380.4
Description: EPCAM Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 267 amino acids (24-265 a.a.) and having a molecular mass of 30.1kDa.;EPCAM is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

SEB283Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

SEB283Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

SEB283Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

SEB283Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Human Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit

4-SEB283Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Epithelial Cell Adhesion Molecule (EPCAM) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Prostate Specific Antigen Std Grade Antigen

VAng-Cr3891-1mg 1 mg
EUR 604.8
Description: Prostate Specific Antigen Std Grade Antigen, Host/Source: Human Seminal Fluid. The purity is detected by salt precipitation.

Epithelial Membrane Antigen (MUC1) Antibody

20-abx121644
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Epithelial Membrane Antigen (MUC1) Antibody

20-abx123255
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Epithelial Membrane Antigen (MUC1) Antibody

20-abx133246
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Epithelial Membrane Antigen (MUC1) Antibody

abx020564-1mg 1 mg
EUR 1011.6

Epithelial Membrane Antigen (MUC1) Antibody

abx020565-1mg 1 mg
EUR 961.2

Epithelial Membrane Antigen (MUC1) Antibody

abx020566-1mg 1 mg
EUR 1011.6

Epithelial Membrane Antigen (MUC1) Antibody

abx020567-1mg 1 mg
EUR 1011.6

Epithelial Membrane Antigen (MUC1) Antibody

abx020569-1mg 1 mg
EUR 961.2

Epithelial Membrane Antigen (MUC1) Antibody

abx020571-1mg 1 mg
EUR 961.2

Epithelial Membrane Antigen (EMA) Antibody

abx022470-02mg 0.2 mg
EUR 1128

Epithelial Membrane Antigen (MUC1) Antibody

abx023797-1mg 1 mg
EUR 1011.6

Epithelial Membrane Antigen (MUC1) Antibody

abx025382-400ul 400 ul
EUR 627.6

Epithelial Membrane Antigen (MUC1) Antibody

abx025382-80l 80 µl
EUR 343.2

Epithelial Membrane Antigen (MUC1) Antibody

abx235427-100ug 100 ug
EUR 661.2

Epithelial Membrane Antigen (MUC1) Antibody

abx235428-100ug 100 ug
EUR 661.2

Mouse Anti-Human Ep-CAM/Epithelial Specific Antigen monoclonal antibody, clone JID678

CABT-L2933-100uL500uL 100 uL, 500 uL
EUR 602.4

Prostate Specific Antigen Antibody

49127-100ul 100ul
EUR 399.6

Prostate Specific Antigen Antibody

49127-50ul 50ul
EUR 286.8

Prostate-specific Antigen Antibody

33477-100ul 100ul
EUR 302.4

Prostate-specific Antigen Antibody

33477-50ul 50ul
EUR 224.4

Epithelium Specific Antigen antibody

10R-E126A 50 ug
EUR 501.6
Description: Mouse monoclonal Epithelium Specific Antigen antibody

Prostate-specific antigen Antibody

abx140217-01mg 0.1 mg
EUR 393.6

Prostate-specific antigen Antibody

abx020585-1mg 1 mg
EUR 577.2

Prostate-specific antigen Antibody

abx020586-1mg 1 mg
EUR 844.8

Prostate-specific antigen Antibody

abx020587-1mg 1 mg
EUR 961.2

Prostate-specific antigen Antibody

abx020588-1mg 1 mg
EUR 961.2

Prostate-specific antigen Antibody

abx020591-1mg 1 mg
EUR 661.2

Prostate-specific antigen Antibody

abx020592-1mg 1 mg
EUR 661.2

Prostate-specific antigen Antibody

abx020593-1mg 1 mg
EUR 661.2

Prostate-specific antigen Antibody

abx020594-1mg 1 mg
EUR 661.2

Prostate-specific antigen Antibody

abx020595-1mg 1 mg
EUR 661.2

Prostate-specific antigen Antibody

abx020596-1mg 1 mg
EUR 794.4

Prostate-specific antigen Antibody

abx020597-1mg 1 mg
EUR 610.8

Prostate-specific antigen Antibody

abx020598-1mg 1 mg
EUR 610.8

Prostate-specific antigen Antibody

abx020599-1mg 1 mg
EUR 610.8

Prostate-specific antigen Antibody

abx020600-1mg 1 mg
EUR 610.8

Prostate-specific antigen Antibody

abx020601-1mg 1 mg
EUR 610.8

Prostate-specific antigen Antibody

abx020604-1mg 1 mg
EUR 794.4

Prostate-specific antigen Antibody

abx022531-1mg 1 mg
EUR 777.6

Prostate-specific antigen Antibody

abx022532-1mg 1 mg
EUR 811.2

Gene Expression Modifications in a Mannequin Neuron Cell Line Uncovered to Autoantibodies from Sufferers with Traumatic Mind Damage and/or Sort 2 Diabetes

Traumatic mind damage and grownup sort 2 diabetes mellitus are every related to the late prevalence of accelerated cognitive decline and Parkinson’s illness via unknown mechanisms. Beforehand, we reported elevated circulating agonist autoantibodies concentrating on the 5-hydroxytryptamine 2A receptor in plasma from subsets of Parkinson’s illness, dementia, and diabetic sufferers struggling with microvascular problems.

Right here, we use a mannequin neuron, mouse neuroblastoma (N2A) cell line, to check messenger RNA expression adjustments following transient publicity to traumatic mind damage and/or sort 2 diabetes mellitus plasma harboring agonist 5-hydroxytryptamine 2A receptor autoantibodies.

We now report involvement of the mitochondrial dysfunction pathway and Parkinson’s illness pathways in autoantibody-induced gene expression adjustments occurring in neuroblastoma cells. Useful gene classes upregulated considerably included cell dying, cytoskeleton-microtubule perform, actin polymerization or depolymerization, regulation of cell oxidative stress, mitochondrial perform, immune perform, protein metabolism, and vesicle perform.

Gene classes considerably downregulated included microtubule perform, cell adhesion, neurotransmitter launch, dopamine metabolism synaptic plasticity, upkeep of neuronal differentiation, mitochondrial perform, and cell signaling.

Taken collectively, these outcomes recommend that agonist 5-hydroxytryptamine receptor autoantibodies (which enhance in Parkinson’s illness and different types of neurodegeneration) mediate a coordinating program of gene expression adjustments in a mannequin neuron which predispose to neuro-apoptosis and are linked to human neurodegenerative ailments pathways.

Novel Alzheimer’s illness danger variants recognized based mostly on whole-genome sequencing of APOE ε4 carriers

Alzheimer’s illness (AD) is a progressive neurodegenerative illness related to a fancy genetic etiology. Moreover the apolipoprotein E ε4 (APOE ε4) allele, a couple of dozen different genetic loci related to AD have been recognized via genome-wide affiliation research (GWAS) performed primarily in people of European ancestry.

 

Lately, a number of GWAS carried out in different ethnic teams have proven the significance of replicating research that establish beforehand established danger loci and looking for novel danger loci. APOE-stratified GWAS have yielded novel AD danger loci that may be masked by, or be depending on, APOE alleles.

 

We carried out whole-genome sequencing (WGS) on DNA from blood samples of 331 AD sufferers and 169 aged controls of Korean ethnicity who have been APOE ε4 carriers. Based mostly on WGS information, we designed a custom-made AD chip (cAD chip) for additional evaluation on an impartial set of 543 AD sufferers and 894 aged controls of the identical ethnicity, no matter their APOE ε4 allele standing.

Mixed evaluation of WGS and cAD chip information revealed that SNPs rs1890078 (P = 6.64E-07) and rs12594991 (P = 2.03E-07) in SORCS1 and CHD2 genes, respectively, are novel genetic variants amongst APOE ε4 carriers within the Korean inhabitants.

As well as, 9 doable novel variants that have been uncommon in people of European ancestry however frequent in East Asia have been recognized. This examine demonstrates that APOE-stratified evaluation is vital for understanding the genetic background of AD in numerous populations.

Related articles

mutationdetection

Identification of key gene modules and pathways of human platelet transcriptome

Identification of key gene modules and pathways of human platelet transcriptome in acute myocardial infarction sufferers by way of co-expression community Acute myocardial infarction (AMI) critically threatens human life. On this examine we aimed to systemically analyze the perform of key gene modules in human platelets in AMI. We used weighted gene co-expression community evaluation (WGCNA) […]

Learn More
mutationdetection

immune cell infiltration and immune-related genes in the tumor microenvironment

The impact of chromosomal fusions on 3D genome folding and recombination in the germ line The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of chromosome conformation capture in combination with single-nucleotide polymorphism (SNP) genotyping and […]

Learn More
mutationdetection

fruits from weighted gene co-expression network analysis

The influence of cross-kingdom molecular forensics on genetic privateness Latest advances in metagenomic expertise and computational prediction could inadvertently weaken a person’s cheap expectation of privateness. By way of cross-kingdom genetic and metagenomic forensics, we will already predict at the very least a dozen human phenotypes with various levels of accuracy. There’s additionally rising potential to […]

Learn More

Leave a Reply

Your email address will not be published. Required fields are marked *