immune cell infiltration and immune-related genes in the tumor microenvironment

mutationdetection

The impact of chromosomal fusions on 3D genome folding and recombination in the germ line

The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of chromosome conformation capture in combination with single-nucleotide polymorphism (SNP) genotyping and analysis of crossover events to study how the higher-order chromatin organization and recombination landscapes are affected by chromosomal fusions in the mammalian germ line.

We demonstrate that chromosomal fusions alter the nuclear architecture during meiosis, including an increased rate of heterologous interactions in primary spermatocytes, and alterations in both chromosome synapsis and axis length.

These disturbances in topology were associated with changes in genomic landscapes of recombination, resulting in detectable genomic footprints. Overall, we show that chromosomal fusions impact the dynamic genome topology of germ cells in two ways: (i) altering chromosomal nuclear occupancy and synapsis, and (ii) reshaping landscapes of recombination.

Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of HNSCC with or without HPV infection

Head and neck squamous cell carcinoma (HNSCC) are the sixth most common cancer type in the world. Human papillomavirus (HPV) infection is an emerging risk factor for HNSCC. Immune infiltration of HNSCC is linked to therapeutic results. This article aimed to decide whether variations in HPV status affect immune infiltration, molecular mechanism, and how these results vary in HNSCC patients.

We investigated the tumor-infiltrating immune cells (TIICs) and immune-related gene differences between HPV (+) and HPV (-) HNSCC. The gene expression quantification data of HNSCC and their clinical information were download from the TCGA database. Immune-related genes have been linked to the ImmPort platform.

After analyzed of 22 TIICs in the HNSCC tumor environment by CIBERSORT and further assessment, lower memory B cell and higher T cell regulatory were connected with better HPV (-) HNSCC outcome, higher activated memory CD4 T cell, higher T cell regulatory, and lower activated NK cell were linked with better HPV (+) result.

We finally got five forms of immune genes (CAMP, EDNRB, NTS, CXCL9, LHB) associated with HNSCC progression. Higher expressions of CAMP, EDNRB, and NTS were associated with increased overall survival in HPV (-) patients. Higher expression of CXCL9 and lower expression of LHB contributed to increased overall survival of HPV (+) patients.

There tend to be discrepancies in the cell structure of TIICs and immune-related genes in HPV (-) and HPV (+) HNSCC. These variances are typically too crucial for the therapeutic outcome of the patient and the development of the tumor. In specific, our sample established these candidate immune cells and immune-related genes as candidate reservoirs for further researches.

mutationdetection
mutationdetection

ALK kinase inhibitor-1

T6409-10mg 10mg Ask for price
Description: ALK kinase inhibitor-1

ALK kinase inhibitor-1

T6409-1g 1g Ask for price
Description: ALK kinase inhibitor-1

ALK kinase inhibitor-1

T6409-1mg 1mg Ask for price
Description: ALK kinase inhibitor-1

ALK kinase inhibitor-1

T6409-50mg 50mg Ask for price
Description: ALK kinase inhibitor-1

ALK kinase inhibitor-1

T6409-5mg 5mg Ask for price
Description: ALK kinase inhibitor-1

TAO Kinase inhibitor 1

HY-112136 50mg
EUR 955.2

TAO Kinase inhibitor 1

T16987-10mg 10mg Ask for price
Description: TAO Kinase inhibitor 1

TAO Kinase inhibitor 1

T16987-1g 1g Ask for price
Description: TAO Kinase inhibitor 1

TAO Kinase inhibitor 1

T16987-1mg 1mg Ask for price
Description: TAO Kinase inhibitor 1

TAO Kinase inhibitor 1

T16987-50mg 50mg Ask for price
Description: TAO Kinase inhibitor 1

TAO Kinase inhibitor 1

T16987-5mg 5mg Ask for price
Description: TAO Kinase inhibitor 1

TAO Kinase inhibitor 1

MBS5755584-10mg 10mg
EUR 195

TAO Kinase inhibitor 1

MBS5755584-25mg 25mg
EUR 300

TAO Kinase inhibitor 1

MBS5755584-2mg 2mg
EUR 145

TAO Kinase inhibitor 1

MBS5755584-50mg 50mg
EUR 460

TAO Kinase inhibitor 1

MBS5755584-5mg 5mg
EUR 160

Tpl2 Kinase Inhibitor 1

T17145-10mg 10mg Ask for price
Description: Tpl2 Kinase Inhibitor 1

Tpl2 Kinase Inhibitor 1

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Description: Tpl2 Kinase Inhibitor 1

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Description: Tpl2 Kinase Inhibitor 1

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Description: Tpl2 Kinase Inhibitor 1

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Description: Tpl2 Kinase Inhibitor 1

RIP1 kinase inhibitor 1

T12725-10mg 10mg Ask for price
Description: RIP1 kinase inhibitor 1

RIP1 kinase inhibitor 1

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Description: RIP1 kinase inhibitor 1

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Description: RIP1 kinase inhibitor 1

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Description: RIP1 kinase inhibitor 1

RIP1 kinase inhibitor 1

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Description: RIP1 kinase inhibitor 1

RIP2 kinase inhibitor 1

T12727-10mg 10mg Ask for price
Description: RIP2 kinase inhibitor 1

RIP2 kinase inhibitor 1

T12727-1g 1g Ask for price
Description: RIP2 kinase inhibitor 1

RIP2 kinase inhibitor 1

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Description: RIP2 kinase inhibitor 1

RIP2 kinase inhibitor 1

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Description: RIP2 kinase inhibitor 1

RIP2 kinase inhibitor 1

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Description: RIP2 kinase inhibitor 1

Tie2 kinase inhibitor 1

T6335-10mg 10mg Ask for price
Description: Tie2 kinase inhibitor 1

Tie2 kinase inhibitor 1

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Description: Tie2 kinase inhibitor 1

Tie2 kinase inhibitor 1

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Description: Tie2 kinase inhibitor 1

Tie2 kinase inhibitor 1

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Description: Tie2 kinase inhibitor 1

Tie2 kinase inhibitor 1

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Description: Tie2 kinase inhibitor 1

EGFR kinase inhibitor 1

T63648-10mg 10mg Ask for price
Description: EGFR kinase inhibitor 1

EGFR kinase inhibitor 1

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Description: EGFR kinase inhibitor 1

EGFR kinase inhibitor 1

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Description: EGFR kinase inhibitor 1

EGFR kinase inhibitor 1

T63648-50mg 50mg Ask for price
Description: EGFR kinase inhibitor 1

EGFR kinase inhibitor 1

T63648-5mg 5mg Ask for price
Description: EGFR kinase inhibitor 1

RIP1 kinase inhibitor 1

MBS3844604-10mg 10mg
EUR 1905

RIP1 kinase inhibitor 1

MBS3844604-1mg 1mg
EUR 430

RIP1 kinase inhibitor 1

MBS3844604-5mg 5mg
EUR 1165

RIP1 kinase inhibitor 1

MBS3844604-5x10mg 5x10mg
EUR 8565

RIP2 kinase inhibitor 1

MBS3841571-10mg 10mg
EUR 615

RIP2 kinase inhibitor 1

MBS3841571-50mg 50mg
EUR 1675

RIP2 kinase inhibitor 1

MBS3841571-5mg 5mg
EUR 430

RIP2 kinase inhibitor 1

MBS3841571-5x50mg 5x50mg
EUR 7520

Tpl2 Kinase Inhibitor 1

MBS5755649-25mg 25mg
EUR 1610

Tpl2 Kinase Inhibitor 1

MBS5755649-5x25mg 5x25mg
EUR 7095

RIP1 kinase inhibitor 1

MBS5767491-100mg 100mg
EUR 3280

RIP1 kinase inhibitor 1

MBS5767491-50mg 50mg
EUR 2185

RIP1 kinase inhibitor 1

MBS5767491-5x100mg 5x100mg
EUR 14615

RIP2 kinase inhibitor 1

MBS5767493-5mg 5mg
EUR 915

RIP2 kinase inhibitor 1

MBS5767493-5x5mg 5x5mg
EUR 3970

Pim-1 kinase inhibitor 1

T60972-10mg 10mg Ask for price
Description: Pim-1 kinase inhibitor 1

Pim-1 kinase inhibitor 1

T60972-1g 1g Ask for price
Description: Pim-1 kinase inhibitor 1

Pim-1 kinase inhibitor 1

T60972-1mg 1mg Ask for price
Description: Pim-1 kinase inhibitor 1

Pim-1 kinase inhibitor 1

T60972-50mg 50mg Ask for price
Description: Pim-1 kinase inhibitor 1

Pim-1 kinase inhibitor 1

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Description: Pim-1 kinase inhibitor 1

PDGFRα kinase inhibitor 1

T12396-10mg 10mg Ask for price
Description: PDGFRα kinase inhibitor 1

PDGFRα kinase inhibitor 1

T12396-1g 1g Ask for price
Description: PDGFRα kinase inhibitor 1

PDGFRα kinase inhibitor 1

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Description: PDGFRα kinase inhibitor 1

PDGFRα kinase inhibitor 1

T12396-50mg 50mg Ask for price
Description: PDGFRα kinase inhibitor 1

PDGFRα kinase inhibitor 1

T12396-5mg 5mg Ask for price
Description: PDGFRα kinase inhibitor 1

PDGFRalpha kinase inhibitor 1

MBS3844085-10mg 10mg
EUR 685

PDGFRalpha kinase inhibitor 1

MBS3844085-50mg 50mg
EUR 1915

PDGFRalpha kinase inhibitor 1

MBS3844085-5mg 5mg
EUR 425

PDGFRalpha kinase inhibitor 1

MBS3844085-5x100mg 5x100mg
EUR 16900

PDGFRalpha kinase inhibitor 1

MBS3844085-100mg 100mg
EUR 3755

PDGFRalpha kinase inhibitor 1

MBS5753656-100mg 100mg
EUR 2840

PDGFRalpha kinase inhibitor 1

MBS5753656-25mg 25mg
EUR 1170

PDGFRalpha kinase inhibitor 1

MBS5753656-50mg 50mg
EUR 1905

PDGFRalpha kinase inhibitor 1

MBS5753656-5x100mg 5x100mg
EUR 12620

Pim-1/2 kinase inhibitor 1

T9229-10mg 10mg Ask for price
Description: Pim-1/2 kinase inhibitor 1

Pim-1/2 kinase inhibitor 1

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Description: Pim-1/2 kinase inhibitor 1

Pim-1/2 kinase inhibitor 1

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Description: Pim-1/2 kinase inhibitor 1

Pim-1/2 kinase inhibitor 1

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Description: Pim-1/2 kinase inhibitor 1

Pim-1/2 kinase inhibitor 1

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Description: Pim-1/2 kinase inhibitor 1

Pim-1 kinase inhibitor 2

T62001-10mg 10mg Ask for price
Description: Pim-1 kinase inhibitor 2

Pim-1 kinase inhibitor 2

T62001-1g 1g Ask for price
Description: Pim-1 kinase inhibitor 2

Pim-1 kinase inhibitor 2

T62001-1mg 1mg Ask for price
Description: Pim-1 kinase inhibitor 2

Pim-1 kinase inhibitor 2

T62001-50mg 50mg Ask for price
Description: Pim-1 kinase inhibitor 2

Pim-1 kinase inhibitor 2

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Description: Pim-1 kinase inhibitor 2

Pim-1 kinase inhibitor 3

T61074-10mg 10mg Ask for price
Description: Pim-1 kinase inhibitor 3

Pim-1 kinase inhibitor 3

T61074-1g 1g Ask for price
Description: Pim-1 kinase inhibitor 3

Pim-1 kinase inhibitor 3

T61074-1mg 1mg Ask for price
Description: Pim-1 kinase inhibitor 3

Pim-1 kinase inhibitor 3

T61074-50mg 50mg Ask for price
Description: Pim-1 kinase inhibitor 3

Pim-1 kinase inhibitor 3

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Description: Pim-1 kinase inhibitor 3

Pan-RAF kinase inhibitor 1

T63386-10mg 10mg Ask for price
Description: Pan-RAF kinase inhibitor 1

Pan-RAF kinase inhibitor 1

T63386-1g 1g Ask for price
Description: Pan-RAF kinase inhibitor 1

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T63386-1mg 1mg Ask for price
Description: Pan-RAF kinase inhibitor 1

Pan-RAF kinase inhibitor 1

T63386-50mg 50mg Ask for price
Description: Pan-RAF kinase inhibitor 1

Pan-RAF kinase inhibitor 1

T63386-5mg 5mg Ask for price
Description: Pan-RAF kinase inhibitor 1

EML4-ALK kinase inhibitor 1

T11184-10mg 10mg Ask for price
Description: EML4-ALK kinase inhibitor 1

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T11184-1g 1g Ask for price
Description: EML4-ALK kinase inhibitor 1

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Description: EML4-ALK kinase inhibitor 1

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T11184-50mg 50mg Ask for price
Description: EML4-ALK kinase inhibitor 1

EML4-ALK kinase inhibitor 1

T11184-5mg 5mg Ask for price
Description: EML4-ALK kinase inhibitor 1

Protein kinase D inhibitor 1

T61163-10mg 10mg Ask for price
Description: Protein kinase D inhibitor 1

Protein kinase D inhibitor 1

T61163-1g 1g Ask for price
Description: Protein kinase D inhibitor 1

Protein kinase D inhibitor 1

T61163-1mg 1mg Ask for price
Description: Protein kinase D inhibitor 1

Protein kinase D inhibitor 1

T61163-50mg 50mg Ask for price
Description: Protein kinase D inhibitor 1

Protein kinase D inhibitor 1

T61163-5mg 5mg Ask for price
Description: Protein kinase D inhibitor 1

EML4-ALK kinase inhibitor 1

MBS5766584-10mg 10mg
EUR 700

EML4-ALK kinase inhibitor 1

MBS5766584-1mg 1mg
EUR 280

EML4-ALK kinase inhibitor 1

MBS5766584-25mg 25mg
EUR 1360

EML4-ALK kinase inhibitor 1

MBS5766584-50mg 50mg
EUR 2065

EML4-ALK kinase inhibitor 1

MBS5766584-5mg 5mg
EUR 420

Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1A (cip1) Antibody

abx345851-100l 100 µl
EUR 350

Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1A (cip1) Antibody

abx345851-50l 50 µl
EUR 250

AKT Kinase Inhibitor

A3150-10 10 mg
EUR 1363.2
Description: AKT Kinase Inhibitor

AKT Kinase Inhibitor

A3150-5 5 mg
EUR 819.6
Description: AKT Kinase Inhibitor

AKT Kinase Inhibitor

A3150-5.1 10 mM (in 1mL DMSO)
EUR 895.2
Description: AKT Kinase Inhibitor

AKT Kinase Inhibitor

HY-10249A 10mg
EUR 1052.4

AKT Kinase Inhibitor

T10276-10mg 10mg Ask for price
Description: AKT Kinase Inhibitor

AKT Kinase Inhibitor

T10276-1g 1g Ask for price
Description: AKT Kinase Inhibitor

AKT Kinase Inhibitor

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Description: AKT Kinase Inhibitor

AKT Kinase Inhibitor

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Description: AKT Kinase Inhibitor

Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage

The evolutionary pressure of endemic malaria and other erythrocytic pathogens has shaped variation in genes encoding erythrocyte structural and functional proteins, influencing responses to hemolytic stress during transfusion and disease.

We sought to identify such genetic variants in blood donors by conducting a genome-wide association study (GWAS) of 12,353 volunteer donors, including 1,483 African Americans, 1,477 Asians, and 960 Hispanics, whose stored erythrocytes were characterized by quantitative assays of in vitro osmotic, oxidative, and cold-storage hemolysis.

GWAS revealed 27 significant loci (p<5×10-8), many in candidate genes known to modulate erythrocyte structure, metabolism, and ion channels, including SPTA1, ALDH2, ANK1, HK1, MAPKAPK5, AQP1, PIEZO1, and SLC4A1/Band 3. GWAS of oxidative hemolysis identified variants in antioxidant enzymes including GLRX, GPX4, G6PD, and a novel golgi-transport protein SEC14L4.

Genome wide significant loci were also tested for association with the severity of steady state (baseline) in vivo hemolytic anemia in patients with sickle cell disease, with confirmation of identified SNPs in HBA2, G6PD, PIEZO1, AQP1 and SEC14L4. Many of the identified variants, such as those in G6PD, have previously been shown to impair erythrocyte recovery after transfusion, associate with anemia, or cause rare Mendelian human hemolytic diseases.

Candidate SNPs in these genes, especially in polygenic combinations, may affect RBC recovery after transfusion and modulate disease severity in hemolytic diseases, such as sickle cell disease and malaria.

Incorporating Genomic and Genetic Testing into the Treatment of Metastatic Luminal Breast Cancer

Background: Treatment of patients with luminal metastatic breast cancer (MBC) has become even more complex over the last few years as molecular profiling has begun to alter disease management. It is well accepted that MBC is not curable but is treatable. Today we are able to prolong progression-free survival and partly overall survival with targeted and more individual treatment strategies adjusted according to the molecular subtype.

Summary: Genetic and genomic testing has become therapeutically relevant in luminal MBC and is therefore an integral component within the treatment spectrum. By now, germline testing of BRCABRCAPIK3CA mutations are inevitable elements in disease management and the current state of the art in luminal MBC patients.

Furthermore, testing of ESR1 resistance mutation, ERBB2 mutation, microsatellite instability, and neurotrophic tyrosine receptor kinase (NTRK) gene fusion (mainly in secretory breast cancer) has recently gained increasing attention. However, based on the expanding role of personalized medicine, clinicians are now faced with substantial new challenges and possibly unsuspected possibilities. The following review summarizes current developments in genetic and genomic testing in luminal MBC.

 

Key messages: In luminal MBC genomics have become an integral component within the spectrum of oncological treatment establishing novel therapeutic facilities. Further developments in treatment personalization adjusted according to the molecular subtype should become increasingly important in order to enhance the progress of de-escalation of chemotherapy in luminal MBC. However, based on the expanding role of personalized medicine, clinicians are now faced with substantial new challenges and possibly unsuspected possibilities.

HIV-1 p24 recombinant antigen.

MBS485187-01mg 0.1mg
EUR 300

HIV-1 p24 recombinant antigen.

MBS485187-1mg 1mg
EUR 1300

HIV-1 p24 recombinant antigen.

MBS485187-5x1mg 5x1mg
EUR 5795

HIV Type 1 p24 Antigen ELISA 2.0 (96 Determinations)

0801002 96T
EUR 657.79
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV-1 gag p24 antigen (RECOMBINANT)

HI1A-720-4 50ug
EUR 295

HIV-1 gag p24 antigen (RECOMBINANT)

HI1A-720-5 100ug
EUR 495

HIV-P24 antigen array kit

VArk-Lsx001 unit Ask for price
Description: Fourth-generation HIV immunoassays detect viral p24 protein in the blood.

Human HIV-1 And HIV-2 Antibodies Plus P24 Antigen Fourth-Generation ELISA Kit

abx257575-05mg 0.5 mg Ask for price

Human HIV-1 And HIV-2 Antibodies Plus P24 Antigen Fourth-Generation ELISA Kit

abx257575-100g 100 µg
EUR 468.75

Human HIV-1 And HIV-2 Antibodies Plus P24 Antigen Fourth-Generation ELISA Kit

abx257575-1mg 1 mg Ask for price

Recombinant HIV-1 p24 Core Antigen

HIV-277 1 vial
EUR 798.4
Description: Protein

HIV-1 p17-p24 recombinant antigen.

00172-V 1 MG
EUR 850

HIV-1 p17-p24 recombinant antigen.

00172-V-100ugvial 100ug/vial
EUR 150
Description: HIV-1 p17-p24 recombinant antigen.

HIV-1 p17-p24 recombinant antigen.

MBS485154-01mg 0.1mg
EUR 300

HIV-1 p17-p24 recombinant antigen.

MBS485154-1mg 1mg
EUR 1300

HIV-1 p17-p24 recombinant antigen.

MBS485154-5x1mg 5x1mg
EUR 5795

Antibody against HIV P24 antigen

MBS478168-10mg 10mg
EUR 1560

Antibody against HIV P24 antigen

MBS478168-1mg 1mg
EUR 275

Antibody against HIV P24 antigen

MBS478168-20mg 20mg
EUR 2570

Antibody against HIV P24 antigen

MBS478168-50mg 50mg
EUR 6185

Antibody against HIV P24 antigen

MBS478168-5mg 5mg
EUR 840

Antibody against HIV P24 antigen

MBS478169-10mg 10mg
EUR 1560

Antibody against HIV P24 antigen

MBS478169-1mg 1mg
EUR 275

Antibody against HIV P24 antigen

MBS478169-20mg 20mg
EUR 2570

Antibody against HIV P24 antigen

MBS478169-50mg 50mg
EUR 6185

Antibody against HIV P24 antigen

MBS478169-5mg 5mg
EUR 840

Antibody against HIV P24 antigen

MBS478170-10mg 10mg
EUR 1560

Antibody against HIV P24 antigen

MBS478170-1mg 1mg
EUR 275

Antibody against HIV P24 antigen

MBS478170-20mg 20mg
EUR 2570

Antibody against HIV P24 antigen

MBS478170-50mg 50mg
EUR 6185

Antibody against HIV P24 antigen

MBS478170-5mg 5mg
EUR 840

Antibody against HIV P24 antigen

MBS478171-10mg 10mg
EUR 1560

Antibody against HIV P24 antigen

MBS478171-1mg 1mg
EUR 275

Antibody against HIV P24 antigen

MBS478171-20mg 20mg
EUR 2570

Antibody against HIV P24 antigen

MBS478171-50mg 50mg
EUR 6185

Antibody against HIV P24 antigen

MBS478171-5mg 5mg
EUR 840

HIV-1 GAG P24 Recombinant Antigen

00111-V-01mg 0,1 mg
EUR 321
Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

HIV-1 GAG P24 Recombinant Antigen

00111-V-1000ug 1000 ug
EUR 1539
Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

HIV 1 p24 core recombinant antigen.

00177-V 1 MG
EUR 850

HIV 1 p24 core recombinant antigen

00177-V-01mg 0,1 mg
EUR 321
Description: HIV 1 p24 core recombinant antigen.

HIV 1 p24 core recombinant antigen

00177-V-1000ug 1000 ug
EUR 1539
Description: HIV 1 p24 core recombinant antigen.

HIV 1 p24 core recombinant antigen.

00177-V-100ugvial 100ug/vial
EUR 150
Description: HIV 1 p24 core recombinant antigen.

HIV 1 p24 core recombinant antigen.

MBS485109-01mg 0.1mg
EUR 300

HIV 1 p24 core recombinant antigen.

MBS485109-1mg 1mg
EUR 1300

HIV 1 p24 core recombinant antigen.

MBS485109-5x1mg 5x1mg
EUR 5795

HIV Type 1 p24 Antigen ELISA (5 X 96 Determinations)

0801200 5 X 96T
EUR 2563

HIV Type 1 p24 Antigen ELISA (5 X 96 Determinations)

801200 5 X 96 Determinations
EUR 2563

Recombinant HIV-1 p24 Antigen, His-tagged

HIV-276 1 vial
EUR 798.4
Description: Protein

Recombinant HIV-1 p24 Antigen, His-tagged

HIV-281 1 vial
EUR 798.4
Description: Protein

HIV Type 1 p24 Antigen ELISA 2.0 (5 X 96 Determinations)

0801008 5 X 96T
EUR 2505

Human HIV(1+2 antibodies plus p24 antigen (4th Generation) ELISA Kit

EH4101 96T
EUR 571.5
Description: Method of detection: Qualitative ;Reacts with: Homo sapiens;Sensitivity: Qualitative

Mouse Anti Human Immunodeficiency Virus (HIV-1) p24 (1947)

MAB12321-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for HIV-1 p24

Mouse Anti Human Immunodeficiency Virus (HIV-1) p24 (1947)

MAB12321-500 0.5
EUR 671.04
Description: Mouse monoclonal antibody specific for HIV-1 p24

HIV-1 gag p24 antigen IgG fraction (monoclonal)

HI1M-721-5 100ug
EUR 425

Human Immunodeficiency Virus (HIV) p24 Antigen >95%

MBS568670-1mg 1mg
EUR 2175

Human Immunodeficiency Virus (HIV) p24 Antigen >95%

MBS568670-5x1mg 5x1mg
EUR 9585

Recombinant HIV-1 p24 Antigen, GST-tagged, HRP-Labled

HIV-282 1 vial
EUR 798.4
Description: Protein

Rat HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614549-10x96StripWells 10x96-Strip-Wells
EUR 3290

Rat HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614549-48StripWells 48-Strip-Wells
EUR 295

Rat HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614549-5x96StripWells 5x96-Strip-Wells
EUR 1800

Rat HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614549-96StripWells 96-Strip-Wells
EUR 450

Goat HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614545-10x96StripWells 10x96-Strip-Wells
EUR 3545

Goat HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614545-48StripWells 48-Strip-Wells
EUR 310

Goat HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614545-5x96StripWells 5x96-Strip-Wells
EUR 1940

Goat HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614545-96StripWells 96-Strip-Wells
EUR 475

Human HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

NSL1389Hu 96 wells
EUR 468

Mouse HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614547-10x96StripWells 10x96-Strip-Wells
EUR 3290

Mouse HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614547-48StripWells 48-Strip-Wells
EUR 295

Mouse HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614547-5x96StripWells 5x96-Strip-Wells
EUR 1800

Mouse HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614547-96StripWells 96-Strip-Wells
EUR 450

Human HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2602892-10x96StripWells 10x96-Strip-Wells
EUR 3040

Human HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2602892-48StripWells 48-Strip-Wells
EUR 285

Human HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2602892-5x96StripWells 5x96-Strip-Wells
EUR 1670

Human HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2602892-96StripWells 96-Strip-Wells
EUR 405

Human HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

EIA06774h each
EUR 430

Bovine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2610168-10x96StripWells 10x96-Strip-Wells
EUR 3545

Bovine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2610168-48StripWells 48-Strip-Wells
EUR 310

Bovine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2610168-5x96StripWells 5x96-Strip-Wells
EUR 1940

Bovine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2610168-96StripWells 96-Strip-Wells
EUR 475

Canine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614543-10x96StripWells 10x96-Strip-Wells
EUR 3545

Canine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614543-48StripWells 48-Strip-Wells
EUR 310

Canine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614543-5x96StripWells 5x96-Strip-Wells
EUR 1940

Canine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614543-96StripWells 96-Strip-Wells
EUR 475

Rabbit HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614550-10x96StripWells 10x96-Strip-Wells
EUR 3545

Rabbit HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614550-48StripWells 48-Strip-Wells
EUR 310

Rabbit HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614550-5x96StripWells 5x96-Strip-Wells
EUR 1940

Rabbit HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614550-96StripWells 96-Strip-Wells
EUR 475

Chicken HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614544-10x96StripWells 10x96-Strip-Wells
EUR 3545

Chicken HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614544-48StripWells 48-Strip-Wells
EUR 310

Chicken HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614544-5x96StripWells 5x96-Strip-Wells
EUR 1940

Chicken HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614544-96StripWells 96-Strip-Wells
EUR 475

Porcine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614548-10x96StripWells 10x96-Strip-Wells
EUR 3545

Porcine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614548-48StripWells 48-Strip-Wells
EUR 310

Porcine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614548-5x96StripWells 5x96-Strip-Wells
EUR 1940

Porcine HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614548-96StripWells 96-Strip-Wells
EUR 475

Recombinant HIV-1 gag p17 and p24 Antigen, GST-tagged

PT2-332 1 vial
EUR 798.4
Description: Protein

Recombinant HIV-1 p24 gag Antigen, beta-galactosidase-tagged

HIV-278 1 vial
EUR 798.4
Description: Protein

Human Immunodeficiency Virus p24 Protein [HIV-1/Clade B]

REC31743-100 0.1
EUR 496.27
Description: Recombinant HIV p24 protein (NCBI accession number ABO61536, AA35-265, L40I) produced in HEK293 cells. Protein carries a C-terminal His-tag.. Protein was purified by immobilised metal affinity and ion exchange chromatography from the pellet of transfected cells.

Human Immunodeficiency Virus p24 Protein [HIV-1/Clade B]

REC31743-500 0.5
EUR 1363.78
Description: Recombinant HIV p24 protein (NCBI accession number ABO61536, AA35-265, L40I) produced in HEK293 cells. Protein carries a C-terminal His-tag.. Protein was purified by immobilised metal affinity and ion exchange chromatography from the pellet of transfected cells.

Human Immunodeficiency Virus P24 Protein [HIV-1/Clade C]

REC31706-100 0.1
EUR 457.08
Description: Recombinant HIV-1 p24 produced in E. coli with a 6x histidine tag.

Human Immunodeficiency Virus P24 Protein [HIV-1/Clade C]

REC31706-500 0.5
EUR 1167.82
Description: Recombinant HIV-1 p24 produced in E. coli with a 6x histidine tag.

Bovine HIV-1 p24 core protein(HIV-1 p24) Anti-body ELISA Kit

NSL1181Bo 96 T
EUR 528

Guinea pig HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614546-10x96StripWells 10x96-Strip-Wells
EUR 3545

Guinea pig HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614546-48StripWells 48-Strip-Wells
EUR 310

Guinea pig HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614546-5x96StripWells 5x96-Strip-Wells
EUR 1940

Guinea pig HIV-1 p24 core protein (HIV-1 p24) antibody ELISA Kit

MBS2614546-96StripWells 96-Strip-Wells
EUR 475

HIV-1 p24 ELISA Kit

Z7040001 1 kit
EUR 865

HIV-1 p24 ELISA Kit

MBS412756-5x960Tests 5x960Tests
EUR 17580

HIV-1 p24 ELISA Kit

MBS412756-960Tests 960Tests
EUR 3770

HIV-1 p24 ELISA Kit

MBS412756-96Tests 96Tests
EUR 510

Recombinant HIV-1 p24 Antigen, beta-galactosidase-tagged, Biotin-Labled

HIV-280 1 vial
EUR 798.4
Description: Protein

Recombinant HIV-1 gag p17-p24 and gp41-gp120 Antigen

VAC-0333 0.5ml
EUR 1598.4
Description: Protein

OPEF01414-1MG - Recombinant Human Immunodeficiency Virus 1 (HIV 1-p24) Antigen

OPEF01414-1MG 1mg
EUR 2216

Recombinant HIV-1 gag p17, p24 and gp120 Antigen, GST-tagged

THP-0332 1 vial
EUR 2398.4
Description: Protein

Human HIV (1+2) antigen&antibody ELISA Kit

EK11777 96Т
EUR 799

Human HIV (1+2) antigen&antibody ELISA Kit

AE62582HU-48Tests 48 Tests
EUR 360
Description: Human (Homo sapiens)

Human HIV (1+2) antigen&antibody ELISA Kit

AE62582HU-96Tests 96 Tests
EUR 680
Description: Human (Homo sapiens)

Human HIV (1+2) antigen&antibody ELISA Kit

AE62582HU-48T 48T
EUR 360
Description: Human (Homo sapiens)

Human HIV (1+2) antigen&antibody ELISA Kit

AE62582HU-96T 96T
EUR 680
Description: Human (Homo sapiens)

Human HIV (1+2) antigen&antibody ELISA Kit

MBS2800305-10x96StripWells 10x96-Strip-Wells
EUR 6840

Human HIV (1+2) antigen&antibody ELISA Kit

MBS2800305-48StripWells 48-Strip-Wells
EUR 480

Human HIV (1+2) antigen&antibody ELISA Kit

MBS2800305-5x96StripWells 5x96-Strip-Wells
EUR 3610

Human HIV (1+2) antigen&antibody ELISA Kit

MBS2800305-96StripWells 96-Strip-Wells
EUR 805

Human HIV (1+2) Antigen & Antibody ELISA Kit

MBS3802470-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human HIV (1+2) Antigen & Antibody ELISA Kit

MBS3802470-48StripWells 48-Strip-Wells
EUR 550

Human HIV (1+2) Antigen & Antibody ELISA Kit

MBS3802470-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human HIV (1+2) Antigen & Antibody ELISA Kit

MBS3802470-96StripWells 96-Strip-Wells
EUR 765

HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

00111-V 1 MG
EUR 850

HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

00111-V-100ugvial 100ug/vial
EUR 150
Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

MBS485158-01mg 0.1mg
EUR 300

HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

MBS485158-1mg 1mg
EUR 1300

HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa

MBS485158-5x1mg 5x1mg
EUR 5795

Extended Range HIV-1 p24 ELISA Kit

MBS412758-5x96Samples 5x96Samples
EUR 2575

Extended Range HIV-1 p24 ELISA Kit

MBS412758-96Samples 96Samples
EUR 560

HIV-1 p24 (group O, strain BCF06) Antibody, Rabbit Pab, Antigen Affinity Purified

MBS8119499-002mL 0.02mL
EUR 185

HIV-1 p24 (group O, strain BCF06) Antibody, Rabbit Pab, Antigen Affinity Purified

MBS8119499-01mL 0.1mL
EUR 385

HIV-1 p24 (group O, strain BCF06) Antibody, Rabbit Pab, Antigen Affinity Purified

MBS8119499-5x01mL 5x0.1mL
EUR 1590

HIV-1 p17/24/gp120 antigen

00169-V-01mg 0,1 mg
EUR 321
Description: HIV-1 p17/24/gp120 antigen.The protein contains the HIV immunodominant regions from gag p17-p24 gp 120.

HIV-1 p17/24/gp120 antigen

00169-V-1000ug 1000 ug
EUR 1539
Description: HIV-1 p17/24/gp120 antigen.The protein contains the HIV immunodominant regions from gag p17-p24 gp 120.

HIV-1 nef antigen

GWB-633F8F 0.5 mg Ask for price

HIV-1 gag p17 antigen (RECOMBINANT)

HI1A-710-4 50ug
EUR 295

HIV-1 gag p17 antigen (RECOMBINANT)

HI1A-710-5 100ug
EUR 495

HIV-1 gag p55 antigen (RECOMBINANT)

HI1A-730-4 50ug
EUR 295

HIV-1 gag p55 antigen (RECOMBINANT)

HI1A-730-5 100ug
EUR 495

HIV-1 p24 (HIV-1)

GWB-420F7B 0.1 mg Ask for price

Recombinant HIV-1 p55 gag Antigen

HIV-283 1 vial
EUR 798.4
Description: Protein

Recombinant HIV-1 p66 pol Antigen

HIV-284 1 vial
EUR 798.4
Description: Protein

HIV-1 envelope p31 antigen (RECOMBINANT)

HI1A-700-4 50ug
EUR 295

HIV-1 envelope p31 antigen (RECOMBINANT)

HI1A-700-5 100ug
EUR 495

HIV-1 intergase antigen

00199-V-01mg 0,1 mg
EUR 321
Description: HIV-1 intergase antigen. The protein contains the HIV-1 immunodominant regions from pol protein (integrase).

HIV-1 intergase antigen

00199-V-1000ug 1000 ug
EUR 1539
Description: HIV-1 intergase antigen. The protein contains the HIV-1 immunodominant regions from pol protein (integrase).

HIV-1 (group M, subtype B, strain 92418) p24 Antibody, Rabbit PAb, Antigen Affinity Purified

MBS8105664-002mL 0.02mL
EUR 185

HIV-1 (group M, subtype B, strain 92418) p24 Antibody, Rabbit PAb, Antigen Affinity Purified

MBS8105664-01mL 0.1mL
EUR 385

HIV-1 (group M, subtype B, strain 92418) p24 Antibody, Rabbit PAb, Antigen Affinity Purified

MBS8105664-5x01mL 5x0.1mL
EUR 1590

HIV-1 Recombinant antigen

MBS320616-01mg 0.1mg
EUR 440

HIV-1 Recombinant antigen

MBS320616-5x01mg 5x0.1mg
EUR 1885

HIV-1 Recombinant antigen

MBS320617-01mg 0.1mg
EUR 440

HIV-1 Recombinant antigen

MBS320617-5x01mg 5x0.1mg
EUR 1885

HIV-1 Recombinant antigen

MBS320618-01mg 0.1mg
EUR 630

HIV-1 Recombinant antigen

MBS320618-5x01mg 5x0.1mg
EUR 2745

HIV-1 p24 Antibody

20-abx137062
  • Ask for price
  • Ask for price
  • 0.5 mg
  • 1 mg

HIV-1 p24 Antibody

abx023925-1mg 1 mg
EUR 828

HIV-1 p24 Antibody

abx023926-1mg 1 mg
EUR 828

HIV-1 p24 Antibody

abx021869-1mg 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021870-1mg 1 mg
EUR 760.8

HIV-1 p24 Antibody

abx021871-1mg 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021872-1mg 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021873-1mg 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021882-1mg 1 mg
EUR 1178.4

HIV-1 p24 Antibody

abx021883-1mg 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021886-1mg 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021887-1mg 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021888-1mg 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx023027-1ml 1 ml
EUR 693.6

HIV-1 p24 Antibody

7313-002mg 0.02 mg
EUR 206.18
Description: HIV-1 p24 Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 is the major capsid protein of the virus and has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different strains.

HIV-1 p24 Antibody

7313-01mg 0.1 mg
EUR 523.7
Description: HIV-1 p24 Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 is the major capsid protein of the virus and has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different strains.

HIV-1 p24, Antibody

GWB-3B2FFB 1 mg Ask for price

HIV-1 p24 Antibody

GWB-26647C 0.1 mg Ask for price

HIV-1 p24, Antibody

GWB-2D04FA 0.1 mg Ask for price

HIV-1 p24, Antibody

GWB-2DD7E0 0.1 mg Ask for price

HIV-1 p24, Antibody

GWB-192382 0.1 mg Ask for price

HIV-1 p24 Antibody

GWB-846CEC 1 ml Ask for price

HIV-1 p24, Antibody

GWB-9C0291 0.1 mg Ask for price

HIV-1 p24 Antibody

GWB-9EAC4B 1 ml Ask for price

HIV-1 p24 Antibody

GWB-4CB110 1 ml Ask for price

HIV-1 p24 Antibody

GWB-76A9C7 0.1 mg Ask for price

HIV-1 p24 Antibody

GWB-F48F6D 0.1 mg Ask for price

HIV-1 p24, Antibody

GWB-B0158C 0.1 mg Ask for price

HIV-1 p24 Antibody

GWB-BBDE10 1 ml Ask for price

HIV-1 p24 Antibody

GWB-F1D71D 0.1 mg Ask for price

 

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