antigen

mutationdetection

The dissection of R genes and locus Pc5.1 in Phytophthora capsici

Bioinformatics evaluation and identification of genes and molecular pathways in steroid-induced osteonecrosis of the femoral head Background: Steroid-induced osteonecrosis of the femoral head (ONFH) is a typical hip joint illness and is troublesome to be identified early. At current, the pathogenesis of steroid-induced ONFH stays unclear, and acknowledged and efficient diagnostic biomarkers are poor. The current research […]

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mutationdetection

signatures of positive selection in cytochrome b gene

Trying to find signatures of optimistic choice in cytochrome b gene related to subterranean life-style in fast-evolving arvicolines (Arvicolinae, Cricetidae, Rodentia) Background: Mitochondrial genes encode proteins concerned in oxidative phosphorylation. Variations in life-style and ecological area of interest could be immediately mirrored in metabolic efficiency. Subterranean rodents characterize a very good mannequin for testing hypotheses on adaptive evolution […]

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mutationdetection

immune cell infiltration and immune-related genes in the tumor microenvironment

The impact of chromosomal fusions on 3D genome folding and recombination in the germ line The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of chromosome conformation capture in combination with single-nucleotide polymorphism (SNP) genotyping and […]

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